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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">endofocus</journal-id><journal-title-group><journal-title xml:lang="ru">FOCUS Эндокринология</journal-title><trans-title-group xml:lang="en"><trans-title>FOCUS. Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-0177</issn><issn pub-type="epub">2713-0185</issn><publisher><publisher-name>ООО "Издательство "Перо"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.62751/2713-0177-2024-5-4-14</article-id><article-id custom-type="elpub" pub-id-type="custom">endofocus-108</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Количественная оценка висцерального жироотложения: сравнение традиционной и локальной биоимпедансометрии в абдоминальной области</article-title><trans-title-group xml:lang="en"><trans-title>Quantification of visceral fat deposition: Comparison of conventional and local bioimpedancemetry in the abdominal region</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3321-7575</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бондарева</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bondareva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бондарева Эльвира Александровна – к.б.н.</p><p>Москва</p></bio><bio xml:lang="en"><p>Elvira A. Bondareva – PhD</p><p>Moscow</p></bio><email xlink:type="simple">antropogenetiki@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7895-6887</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Парфентьева</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Parfenteva</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Парфентьева Ольга Ивановна – к.б.н.</p><p>Москва</p></bio><bio xml:lang="en"><p>Olga I. Parfenteva – PhD</p><p>Moscow</p></bio><email xlink:type="simple">parfenteva.olga@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2557-5647</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаджиахмедова</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gadzhiakhmedova</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гаджиахмедова Аида Нурмагомедовна – клинический ординатор</p><p>Москва</p></bio><bio xml:lang="en"><p>Aida N. Gadzhiakhmedova – Clinical resident</p><p>Moscow</p></bio><email xlink:type="simple">ai.kidman@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6314-4883</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Генерозов</surname><given-names>Э. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Generozov</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Генерозов Эдуард Викторович – к.б.н., доцент</p><p>Москва</p></bio><bio xml:lang="en"><p>Eduard V. Generozov – PhD, Associate Professor</p><p>Moscow</p></bio><email xlink:type="simple">generozov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8077-9381</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазурина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazurina</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мазурина Наталия Валентиновна – д.м.н.; вед. науч. сотр. отдела терапевтической эндокринологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Natalya V. Mazurina – MD, PhD</p><p>Moscow</p></bio><email xlink:type="simple">natalyamazurina@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6220-4397</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ершова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ershova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ершова Екатерина Владимировна – к.м.н.; вед. науч. сотр. отдела терапевтической эндокринологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Ekaterina V. Ershova – MD, PhD</p><p>Moscow</p></bio><email xlink:type="simple">yu99pol06@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6624-2374</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комшилова</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Komshilova</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Комшилова Ксения Андреевна – к.м.н., врач-эндокринолог</p><p>Москва</p></bio><bio xml:lang="en"><p>Kseniya A. Komshilova – PhD</p><p>Moscow</p></bio><email xlink:type="simple">Komshilova.Kseniya@endocrincentr.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8520-8702</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трошина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Troshina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трошина Екатерина Анатольевна – д.м.н., член-корр. РАН, профессор, директор Института клинической эндокринологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Ekaterina A. Troshina – MD, PhD, Professor</p><p>Moscow</p></bio><email xlink:type="simple">troshina@inbox.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФКНЦ Физико-химической медицины им. академика Ю.М. Лопухина Федерального медико-биологического агентства</institution></aff><aff xml:lang="en"><institution>Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical Biological Agency</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГНЦ РФ ФГБУ «Национальный медицинский исследовательский центр эндокринологии» Минздрава России</institution></aff><aff xml:lang="en"><institution>Endocrinology Research Center</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>25</day><month>12</month><year>2024</year></pub-date><volume>5</volume><issue>4</issue><fpage>11</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бондарева Э.А., Парфентьева О.И., Гаджиахмедова А.Н., Генерозов Э.В., Мазурина Н.В., Ершова Е.В., Комшилова К.А., Трошина Е.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Бондарева Э.А., Парфентьева О.И., Гаджиахмедова А.Н., Генерозов Э.В., Мазурина Н.В., Ершова Е.В., Комшилова К.А., Трошина Е.А.</copyright-holder><copyright-holder xml:lang="en">Bondareva E.A., Parfenteva O.I., Gadzhiakhmedova A.N., Generozov E.V., Mazurina N.V., Ershova E.V., Komshilova K.A., Troshina E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://endofocus.elpub.ru/jour/article/view/108">https://endofocus.elpub.ru/jour/article/view/108</self-uri><abstract><sec><title>Цель</title><p>Цель. Анализ связей локальных отведений биоимпедансометрии с количественными показателями висцерального жироотложения, полученными различными косвенными методами.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Программа включала измерение антропометрических признаков и определение состава тела с помощью традиционной  (октополярной  для  770InBody  и  тетраполярной  для  АВС-02  «Медасс»)  и  локальной  биоимпедансометрии в абдоминальной области (АВС-02 «Медасс»). Анализатор 770InBody использовался для оценки площади висцерального жира (VFA), а АВС-02 «Медасс» – для локальных импедансов в подкожном (Z_sc) и висцеральном (Z_visc) отведениях.</p></sec><sec><title>Результаты</title><p>Результаты. На базе ГНЦ РФ ФГПУ «Национальный медицинский исследовательский центр эндокринологии» Минздрава России было проведено одномоментное сплошное исследование. По единой программе обследованы 48 человек (38 женщин и 10 мужчин) в возрасте от 24 до 74 лет. Проведен сравнительный анализ комплекса признаков в подгруппах мужчин и женщин. Половой диморфизм не был выявлен по признакам, характеризующим висцеральное жироотложение (BF10 &lt;3,0). Между признаками наблюдалась положительная зависимость, близкая к линейной; характер связи в подгруппах мужчин и женщин не отличался. Корреляционный анализ выявил сильную связь локальных импедансов с VFA (0,751 [0,594; 0,853] и 0,819 [0,697; 0,895]). Анализ в подгруппах с различным нутритивным статусом выявил значимые различия (p &lt;0,001) по всем исследованным признакам. Подгруппы с ожирением 1 и 2 степени по всем исследованным признакам не отличались, тогда как подгруппы с недостатком массы тела, нормальной массой тела, а также морбидным ожирением демонстрировали значимые различия по изучавшимся параметрам.</p></sec><sec><title>Заключение</title><p>Заключение. Результаты проведенного исследования позволяют заключить, что локальные отведения БИА в абдоминальной области, полученные на отечественном анализаторе, имеют сильную корреляционную связь с другими признаками, характеризующими висцеральное жироотложение (VFA, SAD, ОТ).</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>The aim</title><p>The aim. Analysis of the relationships between local bioimpedance measurements and quantitative estimates of visceral fat deposition obtained by various indirect methods.</p></sec><sec><title>Material and methods</title><p>Material and methods. The program included measurement of anthropometric features and determination of body composition in traditional (octopolar for 770InBody and tetrapolar for ABC-02 Medas) and local schemes in the abdominal area (ABC-02 Medas). The 770InBody analyzer was used to determine the visceral fat area (VFA), and the ABC-02 Medas – for local impedances in the subcutaneous (Z_sc) and visceral (Z_visc) leads.</p></sec><sec><title>Results</title><p>Results. A cross-sectional continuous study was conducted at the National Medical Research Center of Endocrinology of the Ministry of Health of the Russian Federation. A total of 48 people (38 women and 10 men) aged 24 to 74 years were examined using a single program. A comparative analysis of a set of features in the subgroups of men and women was carried out. Sexual dimorphism was not detected for the features characterizing visceral fat deposition (BF10 &lt;3.0). A positive dependence close to linear was observed between the features; the nature of the relationship in the subgroups of men and women did not differ. Correlation analysis revealed a strong relationship between local impedances and VFA (0.751 [0.594; 0.853] and 0.819 [0.697; 0.895]). Analysis in subgroups with different nutritional status revealed significant differences (p &lt;0.001) for all the studied features. Subgroups with grade 1 and 2 obesity do not differ in all studied characteristics, whereas subgroups with underweight, normal body weight, and morbid obesity demonstrate significant differences.</p></sec><sec><title>Conclusion</title><p>Conclusion. The results of the conducted study allow us to conclude that local BIA leads in the abdominal region, obtained on a domestic analyzer, have a strong correlation with other signs characterizing visceral fat deposition (VFA, SAD, WC).</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>подкожное абдоминальное жироотложение</kwd><kwd>висцеральный жир</kwd><kwd>сагиттальный диаметр живота</kwd><kwd>локальная биоимпедансометрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>subcutaneous abdominal fat</kwd><kwd>visceral fat</kwd><kwd>sagittal abdominal diameter</kwd><kwd>local bioimpedancemetry</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Публикация подготовлена в рамках государственного задания «Механизмы дезадаптации двухуровневой системы регуляции аппетита при экзогенно-конституциональном ожирении с множественными осложнениями и способы ее коррекции». Рег. № НИОКТР 122012100180-0</funding-statement><funding-statement xml:lang="en">The publication was prepared within the framework of the State assignment «Mechanisms of maladaptation of the two-level system of appetite regulation in exogenous constitutional obesity with multiple complications and methods of its correction». Reg. No. NIOKTR 122012100180-0</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mitsushio K, Baden MY, Kagisaki T et al. Interrelationships among accumulations of intra- and periorgan fats, visceral fat, and subcutaneous fat. Diabetes. 2024; 73(7): 1122–26. doi: 10.2337/db24-0035.</mixed-citation><mixed-citation xml:lang="en">Mitsushio K, Baden MY, Kagisaki T, et al. Interrelationships Among Accumulations of Intra- and Periorgan Fats, Visceral Fat, and Subcutaneous Fat. 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