endofocusFOCUS ЭндокринологияFOCUS. Endocrinology2713-01772713-0185ООО "Издательство "Перо"10.15829/2713-0177-2023-4-24endofocus-40Research ArticleСтатьиСвязь нейроэндокринных заболеваний с нарушениями снаThe connection of neuroendocrine diseases with sleep disordershttps://orcid.org/0000-0003-1668-8711МисниковаИ. В.MisnikovaI. V.

 д.м.н., профессор, кафедры эндокринологии 

129110, г Москва, ул Щепкина 61\2 

Dr. Sc. (Med.), Professor, Department of Endocrinology 

129110, Moscow, Shchepkina str. 61\2 

inna-misnikova@mail.ruФУВ ГБУЗ МО «Московский областной научно-исследовательский клинический институт имени М. Ф. Владимирского»Moscow Regional Research and Clinical Institute (“MONIKI”)20231812202344Нейроэндокринология2733Copyright © Мисникова И.В., 20242024Мисникова И.В.Misnikova I.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://endofocus.elpub.ru/jour/article/view/40

Большинство физиологических функций организма, включая секрецию гормонов имеет отличия в период сна и бодрствования. Циркадный ритм и гомеостатическое давление сна являются определяющими факторами при засыпании и поддержании сна. Колебания в уровне гормонов во многом определяются циркадными ритмами. Центральные биологические часы, расположенные в супрахиазматическом ядре гипоталамуса, синхронизируются с внешними сигналами, и во многом определяют суточные ритмы секреции гормонов. Многие гормоны могут влиять на дыхательную функцию во время сна, усугубляя апноэ сна при избытке или дефиците их секреции. Нарушения сна могут отмечаться при целом ряде нейроэндокринных заболеваний, ухудшая качество жизни пациентов и, в ряде случаев, способствуя развитию угрожающих жизни осложнений. Скрининг на нарушения сна, в частности активное выявление апноэ сна при акромегалии, гипотиреозе и гиперкортицизме, может значительно снизить риск осложнений при своевременном назначении лечения

Most of the physiological functions of the body, including hormone secretion, differ during sleep and wakefulness. Circadian rhythm and homeostatic sleep pressure are the determining factors in falling asleep and maintaining sleep. Fluctuations in hormone levels are largely determined by circadian rhythms. The central biological clock located in the suprachiasmatic nucleus of the hypothalamus is synchronized with external signals, and largely determines the daily rhythms of hormone secretion. Many hormones can affect respiratory function during sleep, exacerbating sleep apnea when their secretion is excessive or deficient. Sleep disorders can occur in a number of neuroendocrine diseases, worsening the quality of life of patients and, in some cases, contributing to the development of life-threatening complications. Screening for sleep disorders, in particular the active detection of sleep apnea in acromegaly, hypothyroidism and hypercorticism, can significantly reduce the risk of complications with timely treatment.

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The authors declare that there are no conflicts of interest present.