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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">endofocus</journal-id><journal-title-group><journal-title xml:lang="ru">FOCUS Эндокринология</journal-title><trans-title-group xml:lang="en"><trans-title>FOCUS. Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-0177</issn><issn pub-type="epub">2713-0185</issn><publisher><publisher-name>ООО "Издательство "Перо"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/2713-0177-2023-4-27</article-id><article-id custom-type="elpub" pub-id-type="custom">endofocus-61</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Эволюция представлений о диагностике и лечении различных фенотипов хронической сердечной недостаточности при сахарном диабете 2 типа</article-title><trans-title-group xml:lang="en"><trans-title>The evolution of ideas about the diagnosis and treatment of various phenotypes of chronic heart failure in type 2 diabetes mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6385-540X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демидова</surname><given-names>Т. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Demidova</surname><given-names>T. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор, зав. кафедрой эндокринологии лечебного факультета</p><p>117997, г. Москва, ул. Островитянова, д. 1, Тел.: 8 (916) 670-02-12</p><p>Scopus Author ID: 7003771623</p></bio><bio xml:lang="en"><p>Tatyana Yu. Demidova – MD, professor, head of the Department of endocrinology, faculty of general medicine</p><p>ScopusAuthorID: 7003771623</p><p>117997, Moscow, 1 Ostrovityaninova Str.</p></bio><email xlink:type="simple">t.y.demidova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1385-0245</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Измайлова</surname><given-names>М. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Izmailova</surname><given-names>M. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры эндокринологии лечебного факультета</p><p>117997, г. Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Mariam Ya. Izmailova – assistant of the Department of endocrinology, faculty of general medicine</p><p>117997, Moscow, 1 Ostrovityaninova Str.</p></bio><email xlink:type="simple">maremizm@gmail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3656-0312</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лобанова</surname><given-names>К. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Lobanova</surname><given-names>K. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., ассистент кафедры эндокринологии лечебного факультета</p><p>117997, г. Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Kristina G. Lobanova – Can. Sci (med), assistant of the Department of endocrinology, faculty of general medicine</p><p>117997, Moscow, 1 Ostrovityaninova Str.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО РНИМУ им. Н. И. Пирогова Минздрава России</institution></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>18</day><month>12</month><year>2023</year></pub-date><volume>4</volume><issue>4</issue><issue-title>Нейроэндокринология</issue-title><fpage>52</fpage><lpage>63</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Демидова Т.Ю., Измайлова М.Я., Лобанова К.Г., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Демидова Т.Ю., Измайлова М.Я., Лобанова К.Г.</copyright-holder><copyright-holder xml:lang="en">Demidova T.Y., Izmailova M.Y., Lobanova K.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://endofocus.elpub.ru/jour/article/view/61">https://endofocus.elpub.ru/jour/article/view/61</self-uri><abstract><p>Несмотря на успехи, достигнутые в диагностике и лечении, СН независимо от фенотипа остается одной из значимых проблем в сфере здравоохранения, что обусловлено высокой заболеваемостью, частотой госпитализации, инвалидностью и смертностью. В свою очередь, пациенты как с СД 2 типа, так и с преддиабетом являются уязвимой группой в плане развития ХСН. Терапия СН-сФВ на протяжении несколько десятилетий сфокусирована на лечении сопутствующих заболеваний, таких как СД 2 типа, АГ, ИБС, ожирения и при необходимости инициации терапии диуретиками для улучшения качества жизни. Однако, на сегодняшний день достигнут большой прогресс в лечении СН-сФВ. Все руководящие принципы по ведению пациентов с СН на основании результатов крупных рандомизированных исследований постулируют, что иНГЛТ2 типа являются базовыми препаратами для лечения пациентов с СН независимо от ФВ. Алгоритмы специализированной медицинской помощи больным СД рекомендуют назначение иНГЛТ 2 типа при наличии или высоком риске развития ХСН и/или ХБП в независимости от уровня HbA1c пациентам с СД 2 типа для снижения риска госпитализации по поводу СН, сердечно- сосудистых событий и снижения рисков прогрессирования ХБП.</p></abstract><trans-abstract xml:lang="en"><p>Despite the successes achieved in diagnosis and treatment, HF, regardless of the phenotype, remains one of the significant problems in the health sector, due to the high incidence, frequency of hospitalization, disability and mortality. In turn, patients with both type 2 diabetes and prediabetes are a vulnerable group in terms of the development of CHF. CH-sFV therapy has been focused for several decades on the treatment of concomitant diseases such as type 2 diabetes, hypertension, coronary heart disease, obesity and, if necessary, initiation of diuretic therapy to improve the quality of life. However, to date, great progress has been made in the treatment of HF-sFV. All guidelines for the management of patients with HF, based on the results of large randomized trials, postulate that iNGLT2 types are the basic drugs for the treatment of patients with HF, regardless of PV. Algorithms of specialized medical care for patients with diabetes recommend the appointment of iNGLT type 2 in the presence or high risk of developing CHF and/or CKD, regardless of the HbA1c level, in patients with type 2 diabetes to reduce the risk of hospitalization for HF, cardiovascular events and reduce the risks of CKD progression.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая сердечная недостаточность</kwd><kwd>ингиюиторы натрий-глюкозного котранспортера-2</kwd><kwd>сахарный диабет2 типа</kwd><kwd>фракция выброса</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic heart failure</kwd><kwd>sodium-glucose cotransporter-2 inhibitors</kwd><kwd>type 2 diabetes mellitus</kwd><kwd>ejection fraction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Theofilis P, Oikonomou E, Tsioufis K, Tousoulis D. 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