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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">endofocus</journal-id><journal-title-group><journal-title xml:lang="ru">FOCUS Эндокринология</journal-title><trans-title-group xml:lang="en"><trans-title>FOCUS. Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-0177</issn><issn pub-type="epub">2713-0185</issn><publisher><publisher-name>ООО "Издательство "Перо"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.62751/2713-0177-2024-5-4-13</article-id><article-id custom-type="elpub" pub-id-type="custom">endofocus-79</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Диабетический дистресс у пациентов с сахарным диабетом 2 типа с ожирением</article-title><trans-title-group xml:lang="en"><trans-title>Diabetes distress in patients with type 2 diabetes mellitus and obesity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-7983-782X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саргсян</surname><given-names>Э. Ж.</given-names></name><name name-style="western" xml:lang="en"><surname>Sargsyan</surname><given-names>E. Zh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Саргсян Элен Жирайровна – клинический ординатор кафедры эндокринологии ИКМ </p><p>Москва</p><p> </p></bio><bio xml:lang="en"><p>Ellen Zh. Sargsyan – resident of the Department of endocrinology</p><p>Moscow</p></bio><email xlink:type="simple">ellensargsyan98@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6899-4457</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скуридина</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Skuridina</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Скуридина Дарья Викторовна –  ассистент кафедры эндокринологии ИКМ </p><p>Москва</p></bio><bio xml:lang="en"><p>Darya V. Skuridina – assistant at the Department of endocrinology</p><p>Moscow</p></bio><email xlink:type="simple">shurpesha@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>25</day><month>12</month><year>2024</year></pub-date><volume>5</volume><issue>4</issue><fpage>6</fpage><lpage>10</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Саргсян Э.Ж., Скуридина Д.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Саргсян Э.Ж., Скуридина Д.В.</copyright-holder><copyright-holder xml:lang="en">Sargsyan E.Z., Skuridina D.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://endofocus.elpub.ru/jour/article/view/79">https://endofocus.elpub.ru/jour/article/view/79</self-uri><abstract><sec><title>Цель</title><p>Цель. Определить роль ожирения в развитии диабетического дистресса при сахарном диабете 2 типа (СД2), выявить клинико-лабораторные особенности пациентов с наличием этих состояний.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследовании приняли участие 152 человека (72 мужчины и 80 женщин) с СД2: 76 пациентов без ожирения (группа 1) и 76 с ИМТ ≥30 кг/м2 (группа 2). Средний возраст пациентов составил 51 [40; 60] год. Стаж сахарного диабета у исследуемых был менее 10 лет. Всем участникам проводились определение гликированного гемоглобина (НbА1с), окружности талии, диагностика наличия диабетического дистресса с использованием специализированного опросника PAID и оценка депрессивного состояния с помощью шкалы Бека. Статистическая обработка данных выполнялась с применением пакетов программ Microsoft Excel 2016 и STATISTICA.</p></sec><sec><title>Результаты</title><p>Результаты. Пациенты c СД2 и ожирением имеют достоверно более выраженный диабетический дистресс по шкале PAID, более высокий уровень депрессии по шкале Бека, а также достоверно более высокий показатель НbА1с. В группе пациентов с высокой вероятностью диабетического дистресса средний уровень НbА1с был достоверно выше на 0,88%, а окружность талии больше на 8,3 см. По данным корреляционного анализа выявлена прямая корреляционная связь между окружностью талии и количеством баллов по опроснику PAID.</p></sec><sec><title>Заключение</title><p>Заключение. Ожирение при СД2 является фактором риска диабетического дистресса и ассоциировано с более высоким риском развития депрессии. Диабетический дистресс связан с более высокими значениями НbА1с и выраженностью абдоминального ожирения, что ухудшает контроль СД, а значит, может опосредованно увеличивать риск развития осложнений. Понимание диабетического дистресса и эффективные стратегии управления им могут значительно повысить эффективность лечения и улучшить качество жизни пациентов с СД2 и ожирением.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>The aim</title><p>The aim. To determine the role of obesity in the development of diabetic distress in patients with type 2 diabetes, to identify clinical and laboratory features of patients with type 2 diabetes and diabetic distress.</p></sec><sec><title>Material and methods</title><p>Material and methods. 152 patients (72 men and 80 women) with type 2 diabetes participated in the study, 76 of them were non-obese (group 1), 76 had a BMI &gt;30 kg/m2 (group 2). The average age of patients is 51 [40; 60] years. The experience of diabetes mellitus in the studied patients is &lt;10 years. All patients underwent the determination of HbA1c, waist circumference, diagnosis of diabetic distress using a specialized PAID questionnaire and assessment of depression using the Beck scale. Statistical data processing was carried out using the software packages Microsoft Excel 2016 and STATISTICA.</p></sec><sec><title>Results</title><p>Results. Patients with type 2 diabetes and obesity have significantly more pronounced diabetic distress on the PAID scale, a higher level of depression on the Beck scale, as well as a significantly higher index of HbA1c. In the group of patients with a high probability of diabetic distress, the average level of HbA1c was significantly higher by 0.88%, and the waist circumference was 8.3 cm larger. As a result of the correlation analysis, a direct correlation was revealed between waist circumference and the number of points according to the PAID questionnaire.</p></sec><sec><title>Conclusion</title><p>Conclusion. Obesity in type 2 diabetes is a risk factor for diabetic distress and is associated with a higher risk of depression. Diabetic distress is associated with higher values of HbA1c and the severity of abdominal obesity, which worsens the control of diabetes mellitus, which means that it may indirectly increase the risk of complications. Understanding diabetic distress and effective management strategies can significantly improve the effectiveness of treatment and improve the quality of life of patients with type 2 diabetes and obesity.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет 2 типа</kwd><kwd>диабетический дистресс</kwd><kwd>ожирение</kwd><kwd>гипергликемия</kwd><kwd>инсулинорезистентность</kwd><kwd>индекс массы тела</kwd></kwd-group><kwd-group xml:lang="en"><kwd>type 2 diabetes mellitus</kwd><kwd>diabetes distress</kwd><kwd>obesity</kwd><kwd>hyperglycemia</kwd><kwd>insulin resistance</kwd><kwd>body mass index</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">GBD 2021 Diabetes Collaborators. Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: A systematic analysis for the Global Burden of Disease Study 2021. 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