endofocusFOCUS ЭндокринологияFOCUS. Endocrinology2713-01772713-0185ООО "Издательство "Перо"10.62751/2713-0177-2024-5-2-14endofocus-82Research ArticleСтатьиНарушения липидного обмена у пациентов с сахарным диабетом 2 типа: фокус на гипертриглицеридемиюLipid metabolism disorders in patients with type 2 diabetes mellitus: focus on hypertriglyceridemiahttps://orcid.org/0000-0001-6385-540XДемидоваТ. Ю.DemidovaT. Yu.

Демидова Татьяна Юльевна –  д. м. н., профессор, заведующая кафедрой эндокринологии лечебного факультета

117997, Россия, г. Москва, ул. Островитянова, д. 1

Tatiana Yu. Demidova –  D. Sci. (Med.), Prof.

1, Ostrovityanov St., Moscow, 117997

t.y.demidova@gmail.comhttps://orcid.org/0000-0001-5512-6899УшановаФ. О.UshanovaF. O.

Ушанова Фатима Омариевна – к . м. н., доцент кафедры эндокринологии лечебного факультета

117997, Россия, г. Москва, ул. Островитянова, д. 1

Fatima O. Ushanova – C . Sci. (Med.)

1, Ostrovityanov St., Moscow, 117997

fati_2526@mail.ruФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н. И. Пирогова» Минздрава РоссииPirogov Russian National Research Medical University202413052024522530Copyright © Демидова Т.Ю., Ушанова Ф.О., 20242024Демидова Т.Ю., Ушанова Ф.О.Demidova T.Y., Ushanova F.O.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://endofocus.elpub.ru/jour/article/view/82

Распространенность сахарного диабета (СД) растет тревожными темпами во всем мире. Диабетические осложнения являются одной из ведущих причин снижения трудоспособности, заболеваемости и преждевременной смертности. Наряду с хронической гипергликемией, персистирующим системным воспалением на фоне инсулинрезистентности в развитии макрососудистых осложнений СД играет важную роль дислипидемия. Для СД характерно развитие смешанной формы дислипидемии, характеризующейся избыточным накоплением наиболее атерогенных форм липидов. В большинстве случаев при СД 2 типа имеет место гипертриглицеридемия. Наиболее эффективным инструментом коррекции дислипидемии на сегодняшний день является терапия фибратами, в том числе в комбинации со статинами.

The prevalence of diabetes mellitus (DM) is growing at an alarming rate worldwide. Diabetic complications are one of the leading causes of disability, morbidity and premature mortality. Along with chronic hyperglycemia, persistent systemic inflammation on the background of insulin resistance, dyslipidemia plays an important role in the development of macrovascular complications of diabetes. DM is characterized by the development of a mixed form of dyslipidemia, characterized by excessive accumulation of the most atherogenic forms of lipids. In most cases, hypertriglyceridemia occurs in type 2 diabetes. The most effective tool for correcting dyslipidemia today is fibrate therapy, including in combination with statins.

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The authors declare that there are no conflicts of interest present.