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Medical treatment of obesity: Modern approaches and prospects

https://doi.org/10.62751/2713-0177-2024-5-4-18

Abstract

Obesity is a chronic progressive disease that poses a major problem for modern healthcare due to the high and rapidly growing prevalence and development of severe complications such as cardiovascular diseases, type 2 diabetes mellitus, malignant neoplasms, etc. Effective treatment of obesity requires an integrated approach, where drug therapy and, in some cases, bariatric intervention complement lifestyle measures – nutrition correction and the use of regular physical activity. Successful treatment of obesity requires an individual approach to the patient, taking into account the initial body weight, the presence of risk factors or developed concomitant diseases, as well as the dynamics of weight loss during therapy. Drug therapy is an important part of the treatment of obese patients, because it allows you to achieve a more significant result of weight loss, and, importantly, to maintain a reduced weight. Drugs of the GLP-1 agonists, widely used today in the treatment of obesity, not only directly affect body weight, but also reduce the risks of severe cardiovascular diseases and metabolic disorders, thus leading to an improvement in the quality of life and an increase in its duration. The article presents the main approaches to the treatment of obese patients with a description of the modern possibilities of pharmacological treatment of obesity.

About the Authors

V. V. Titova
Pirogov Russian National Research Medical University
Russian Federation

Victoria V. Titova –  assistant at the Department of Endocrinology Medical Faculty

Moscow



F. O. Ushanova
Pirogov Russian National Research Medical University
Russian Federation

Fatima O. Ushanova – Can. Sci. (Med.), Associate Professor of the Department of Endocrinology of the Faculty of Medicine

Moscow



T. Yu. Demidova
Pirogov Russian National Research Medical University
Russian Federation

Tatiana Yu. Demidova – D. Sci. (Med.), Prof.

Moscow



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Review

For citations:


Titova V.V., Ushanova F.O., Demidova T.Yu. Medical treatment of obesity: Modern approaches and prospects. FOCUS. Endocrinology. 2024;5(4):40-48. (In Russ.) https://doi.org/10.62751/2713-0177-2024-5-4-18

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