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FOCUS. Endocrinology

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Comprehensive understanding of stroke risk, prognosis, and preventive strategies for type 2 diabetes

https://doi.org/10.15829/2713-0177-2023-4-25

Abstract

Stroke is a serious and disabling disease with a high mortality rate that is becoming increasingly common worldwide, posing a serious threat to the health and quality of life of patients. Type 2 diabetes plays a special role in increasing the risk of stroke, which not only increases the risk of developing a stroke, but also negatively affects the outcome and the possibility of recurrent strokes.

In order to prevent stroke, systematic action is necessary, including the correction of risk factors and the use of effective medications. One such drug is pioglitazone. Many studies support its effectiveness in reducing the risk of cardiovascular events, including stroke, for both secondary and primary prevention.

Pioglitazone may be particularly beneficial for patients at high risk of cardiovascular disease and those with a history of ischemic brain damage. Despite the known side effects, its benefits in preventing stroke outweigh the possible disadvantages.

This review provides important aspects of the role of type 2 diabetes mellitus in increasing the risk of stroke and discusses the prospects for the use of pioglitazone as a drug therapy affecting stroke risk and prognosis.

About the Authors

T. Yu. Demidova
Pirogov Russian National Research Medical University
Russian Federation

Tatiana Yu. Demidova – Dr. Sc. (Med.), Professor, Head of Endocrinology Department 

1 Ostrovitynova street, 117997 Moscow 



V. V. Titova
Pirogov Russian National Research Medical University
Russian Federation

Victoria V. Titova – assistant of the department of endocrinology medical faculty 

1 Ostrovitynova street, 117997 Moscow 



F. O. Ushanova
Pirogov Russian National Research Medical University
Russian Federation

Fatima O. Ushanova – Cand. Sci. (Med.), assistant of the department of endocrinology medical faculty 

1 Ostrovitynova street, 117997 Moscow 



References

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Review

For citations:


Demidova T.Yu., Titova V.V., Ushanova F.O. Comprehensive understanding of stroke risk, prognosis, and preventive strategies for type 2 diabetes. FOCUS. Endocrinology. 2023;4(4):34-41. (In Russ.) https://doi.org/10.15829/2713-0177-2023-4-25

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ISSN 2713-0177 (Print)
ISSN 2713-0185 (Online)