Ovarian reserve in obese patients: where do the eggs disappear?
https://doi.org/10.62751/2713-0177-2024-5-1-05
Abstract
Currently, the issue of obesity and its impact on various aspects of human health is actively being discussed. The role of obesity in the development of metabolic syndrome is well known. Within the study of the obesity pandemic, the modern medical community is conducting research in the field of reproductive health. In women, markers of ovarian reserve are considered, with the main one being the level of anti-Mullerian hormone (AMH). It is known that with age, the number of AMH and antral follicles in a woman's body decreases. However, there is data in the modern literature indicating a decrease in ovarian reserve parameters in conditions of weight gain. Weight gain is accompanied by a imbalance of adipokines - biologically active substances produced mainly by adipose tissue and other tissues of the body that affect metabolic processes. It can be assumed that a deep study of the relationship between decreased reproductive potential and obesity, timely prevention of metabolic disorders will improve fertility indicators.
About the Authors
K. V. Azizova
I. P. Pavlov First Saint-Petersburg State medical university
Russian Federation
Russian Federation
Karine V. Azizova – postgraduate student of the Faculty Therapy Department with a course in Endocrinology and Cardiology with the Clinic named after Academician G. F. Lang
Saint Petersburg
S. V. Dora
I. P. Pavlov First Saint-Petersburg State medical university
Russian Federation
Russian Federation
Svetlana V. Dora – Doc. Sci. (Med.), Associate Professor of the Department of Faculty Therapy with a course in Endocrinology and Cardiology with the Clinic named after Academician G. F. Lang
Saint Petersburg
Yu. Sh. Khalimov
I. P. Pavlov First Saint-Petersburg State medical university
Russian Federation
Russian Federation
Yuri Sh. Khalimov – Doc. Sci. (Med.), Professor, Head of the Faculty Department of Therapy with a course in Endocrinology and Cardiology with the Clinic named after Academician G. F. Lang
Saint Petersburg
A. R. Volkova
I. P. Pavlov First Saint-Petersburg State medical university
Russian Federation
Russian Federation
Anna R. Volkova – Doc. Sci. (Med.), Professor of the Department of Faculty Therapy with a course in Endocrinology and Cardiology with the Clinic named after Academician G. F. Lang
Saint Petersburg
T. A. Cheboksarova
I. P. Pavlov First Saint-Petersburg State medical university
Russian Federation
Russian Federation
Tatyana A. Cheboksarova – student
Saint Petersburg
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Review
For citations:
Azizova K.V., Dora S.V., Khalimov Yu.Sh., Volkova A.R., Cheboksarova T.A. Ovarian reserve in obese patients: where do the eggs disappear? FOCUS. Endocrinology. 2024;5(1):34-41. (In Russ.) https://doi.org/10.62751/2713-0177-2024-5-1-05
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