Ингибиторы натрий-глюкозных котранспортеров и мозг
https://doi.org/10.15829/2713-0177-2023-4-26
Аннотация
Сахарный диабет (СД) ассоциирован с повышенным риском инсульта и когнитивных нарушений. Проблема профилактики церебральных нарушений при СД не решена. В обзоре представлены современные данные о месте и роли натрий-глюкозных котранспортеров (НГЛТ) в головном мозге, рецепторы которых играют важную роль при ишемически-реперфузионном повреждении головного мозга и нейродегенеративных изменениях. Представлены и обобщены современные исследования, посвященные церебропротекторным эффектам сахароснижающих препаратов – ингибиторов НГЛТ.
Об авторах
К. В. Антонова
ФГБНУ «Научный центр неврологии»
Россия
Россия
д.м.н., врач-эндокринолог, ведущий научный сотрудник 1-го неврологического отделения
125367 Москва, Волоколамское шоссе, 80
М. М. Танашян
ФГБНУ «Научный центр неврологии»
Россия
Россия
д.м.н., профессор, член-корр. РАН, зам. директора по научной работе, руководитель 1-го неврологического отделения
125367 Москва, Волоколамское шоссе, 80
О. В. Лагода
ФГБНУ «Научный центр неврологии»
Россия
Россия
к.м.н., врач-невролог высшей категории, старший научный сотрудник 1-го неврологического отделения
125367 Москва, Волоколамское шоссе, 80
Т. С. Шишкина
ФГБНУ «Научный центр неврологии»
Россия
Россия
ординатор
125367 Москва, Волоколамское шоссе, 80
И. М. Ловчев
ФГБНУ «Научный центр неврологии»
Россия
Россия
ординатор
125367 Москва, Волоколамское шоссе, 80
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Рецензия
Для цитирования:
Антонова К.В., Танашян М.М., Лагода О.В., Шишкина Т.С., Ловчев И.М. Ингибиторы натрий-глюкозных котранспортеров и мозг. FOCUS Эндокринология. 2023;4(4):42-51. https://doi.org/10.15829/2713-0177-2023-4-26
For citation:
Antonova K.V., Tashanyan M.M., Lagoda O.V., Shishkina T.S., Lovchev I.M. Sodium- glucose cotransporter inhibitors and the brain. FOCUS. Endocrinology. 2023;4(4):42-51. (In Russ.) https://doi.org/10.15829/2713-0177-2023-4-26
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